What is Autologous Platelet Rich Plasma (PRP)?

“Autologous Platelet Rich Plasma (PRP) is defined as the volume of plasma in autologous blood with a platelet concentration above baseline.”

Platelets are tiny plate-shaped, colourless bodies which when activated helps release growth factors that work with white blood cells for tissue regeneration. This is where PRP can help to reduce pain, promote and accelerate tissue healing, regenerate and increase collagen deposition.

Application of Platelet Rich Plasma has been evaluated in various medical disciplines including orthopaedics, sports medicine, and wound healing as well as cosmetic, plastic, maxillofacial and cardiothoracic surgery.

What can Platelet Rich Plasma (PRP) Do?

PRP is safe and effective treatment to accelerate wound healing for various injuries. The growth factors released by PRP will have beneficial effects to regenerate tissue, reduce pain and shorten healing time by 40 – 50%.

What Conditions are Platelet Rich Plasma (PRP) used for?

  • Cartilage degradation / worn out
  • Chondromalacia patellae
  • Osteoarthritis
  • Sports injury (e.g. tennis elbow, muscle/ligament tear, etc.)
  • Wound healing for surgeries


PRP is suitable for almost everyone, however, patients with blood disorder or cancer are not recommended to undergo this treatment.

Benefits of Platelet Rich Plasma (PRP)

  • Accelerates wound healing, with shorter downtime, allows patient to return to activities of daily living sooner.
  • Significant reduction of pain through the acceleration of wound healing and activities of the growth factors.
  • With high concentration of leukocytes in PRP, it offers an antimicrobial effect, reducing the risk of infections
  • PRP is developed from Autologous blood, it is therefore inherently safe and free of transmissible diseases such as HIV and hepatitis.

Platelet Rich Plasma (PRP) Procedure

  1. A small amount of blood is drawn from the patient. This step will be similar to blood-taking for any other test.
  2. The blood drawn in this special tube will be centrifuge at high speed to isolate the PRP from red blood cells.
  3. When ready, the PRP will be reintroduced back to the same patient via injection.

When PRP is applied back into the same patient, there will be a release of growth factors which will help to accelerate healing and regeneration.

Ask our specialist today on how PRP can help you. Call (+65) 6471 2674 (24 Hour).

Brief Outline of Knee (Synovial) Plica Injury

The synovial plica is a thin fibrous membrane that is a remnant from the foetal knee development. The plica once divided the knee into three separate compartments during foetal development but then became a part of the knee structure as the compartments became one protective cavitiy. The plica may become inflamed due to friction or pinching between the patella and the femur. This is common when the knee is flexed and placed under a stress.

Anatomy and Physiology for Knee (Synovial) Plica

Knee Synovial Plica

When a foetus is developing, the knee is divided into three compartments. As the foetus reached full development these three compartments become one large protective cavity, the synovial membrane. Most people have some remnant of these divisions, the plica, left over as thin membranes. They are usually located on the medial side of the knee, and extend from the suprapatellar fossa along the medial patellar border. These plica seldom cause problems by themselves. When friction or a pinching between the femur and patella occur, the synovial plica may become inflamed causing it to thicken, which in turn causes more friction creating a vicious cycle.

Cause of Knee (Synovial) Plica

Trauma to the flexed knee. Repetitive stress, especially with medial weight bearing, e.g. biking.

Signs and Symptoms of Knee (Synovial) Plica

Pain. Tenderness over the synovial plica.

Complication If Left Knee (Synovial) Plica Unattended

The synovial plica will continue to become inflamed and limit flexion activity in the knee if left unattended. The pain may also cause a change in gait or running form that could lead to other overuse injuries.

Immediate Treatment For Knee (Synovial) Plica Unattended

Reducing acitivy. R.I.C.E. Anti-inflammatory medication. Shockwave therapy. Anti-inflammatory injection.

Rehabilitation and Prevention For Knee (Synovial) Plica Unattended

Strengthening the quadriceps and hamstrings will take pressure off the synovial plica. Increasing flexibility in these muscles will also relieve pressure that may be irritating the condition. Use of proper equipment, especially running shoes, can eliminate the irritation and force the knee back into proper alignment during activity.

Long-term Prognosis for Knee (Synovial) Plica Unattended

Once pain subsides, a return to normal activity can be expected. Very rarely is arthroscopic surgery required to remove the plica. No adverse effects have been found from the removal of the synovial plica and a complete return to activity can be expected.

Call (+65) 6471 2674 (24 Hour) to see our knee specialist regarding your knee plica today.

Brief Outline of Patellofemoral Pain Syndrome

Pain in the patella (knee cap), especially after sitting for a long time or running downhill, may be a result of a fairly common condition called patellofemoral pain syndrome. The pain may result from incorrect movement of the patella over the femur, or tight tendons. The articular cartilage under the knee cap may become inflamed as well, leading to another condition called chondromalacia patellae. Found more commonly in women.

Anatomy and Physiology of Patellofemoral Pain Syndrome

The patella is small triangular sesamoid bone within the tendon of the quadriceps femoris muscle and forms the front of the knee joint. It is attached above to the quadriceps tendon, and below to the patellar (tendon) ligament, and articulates with the patellofemoral joint. The angle formed between the two lines of pull of the quadroceps muscle and the patellar (tendon) ligament is known as the Q-angle. If the patella moves out of its normal path, even slightly, it can cause irritation and pain. Tight tendons also place pressure on the patella causing inflammation.

Cause of Patellofemoral Pain Syndrome

Incorrect running form or improper shoes. Weak or tight quadriceps. Chronic patella dislocations.

Signs and Symptoms of Patellofemoral Pain Syndrome

Pain on and under the knee cap, and worsens after sitting for extended periods or walking downstairs. Clicking or grinding may be felt when flexing the knee. Dull, aching pain in the center of the knee.

Complications if Left Patellofemoral Pain Syndrome Unattended

The inflammation from this condition if left unattended can worsen and cause more permanent damage to the surrounding structures. If the tendon becomes inflamed, it could eventually rupture. The cartilage under the patella may also become inflamed.

Immediate Treatment for Patellofemoral Pain Syndrome

Rest, which can be simply reducing the intensity and duration. Ice and anti-inflammatory medication. Shockwave Therapy. Anti-inflammatory injection. Physiotherapy.

Rehabilitation and Prevention for Patellofemoral Pain Syndrome

Rehabilitation starts with restoring the strength and flexibility of the quadriceps. When returning to activity after pain has subsided, gradual increases in intensity, limiting repetitive stresses on the knee and proper warm-up techniques will ensure that the pain does not return.

Strong, flexible quadriceps and hamstrings and avoiding overuse will help prevent patellofemoral pain syndrome. A good warm-up before training will also help.

Long-term Prognosis for Patellofemoral Pain Syndrome

With complete treatment there are seldom any lasting effects. If the condition does not respond to treatment, surgical intervention may be necessary.

Call (+65) 6471 2674 (24 Hour) to fix an appointment to treat Patellofemoral Pain Syndrome today.

Brief Outline of Chondromalacia Patellae (Runner’s Knee)

Softening and degeneration of the articular cartilage of the patella (knee cap) in athletes is usually a result of overuse, trauma, or abnormal forces on the knee. In older adults it can be a result of degenerative arthritis. Pain under the knee cap and a grating sensation when the knee is extended are possible signs of this condition.

Anatomy and Physiology of Chondromalacia Patellae (Runner’s Knee)

The underside of the patella is protected by articular (hyaline) cartilage, which is made up of collagen fibres and water. The cartilage can become damaged and softened by repetitive micro-trauma due to overuse or abnormal load bearing on the knee. This degeneration makes the surface rough instead of its usual smooth surface which causes additional inflammation and pain. Generally described in four progressive stages, from softening and blistering, to full cartilage defects and subchondrial bone exposure.

Knee Chondromalacia

Cause of Chondromalacia Patellae (Runner’s Knee)

Repetitive micro-trauma to the cartilage through overuse conditions. Misalignment of the knee cap. Previous fracture or dislocation of the knee cap.

Signs and Symptoms of Chondromalacia Patellae (Runner’s Knee)

Pain that worsens after sitting for prolonged periods or when using stairs or rising from a seated position. Tenderness over the knee cap. Grating or grinding sensation when the knee is extended.

Complications if Left Chondromalacia Patellae (Runner’s Knee) Unattended

Cartilage that degenerates and becomes rough can cause scarring in the bone surface it rubs against. This in turn cause more inflammation. Cartilage can also be torn when it is rough leading to loose bodies in the joint.

Immediate Treatment for Chondromalacia Patellae (Runner’s Knee)

Rest and ice. Anti-inflammatory medication. Synvisc injection.

Rehabilitation and Prevention of Chondromalacia Patellae (Runner’s Knee)

Limiting activity until the pain subsides and gradually re-entering the activity is important. Strengthening and stretching the quadriceps is important to relieve pressure on the patella. Activities that increase the pain, such as deep knee bending, should be avoided until completely pain free. Avoid abnormal stress on the knee, and keep the hamstrings and quadriceps strong and flexible to prevent this condition.

Long-term Prognosis for Chondromalacia Patellae (Runner’s Knee)

Chondromalacia patellae commonly responds well to therapy and anti-inflammatory medication. In rare cases, surgery may be required to correct a misalignment in the knee cap.

Call (+65) 6471 2674 (24 Hour) to fix an appointment with our specialist to treat your chonromalace patellae (runner’s knee) today.